Publications

[5] Nicholas B. Struntz, Andrew Chen, Anja Deutzmann, Robert M. Wilson, Eric Stefan, Helen L. Evans, Maricela A. Ramirez, Tong Liang, Francisco Caballero, Mattheus H. E. Wildschut, Dylan V. Neel, David B. Freeman, Marius S. Pop, Marie McConkey, Sandrine Muller, Brice H. Curtin, Hanna Tseng, Kristen R. Frombach, Vincent L. Butty, Stuart S. Levine, Clementine Feau, Sarah Elmiligy, Jiyoung A. Hong, Timothy A. Lewis, Amedeo Vetere, Paul A. Clemons, Scott E. Malstrom, Benjamin L. Ebert, Charles Y. Lin, Dean W. Felsher, Angela N. Koehler. Stabilization of the Max homodimer with a small molecule attenuates Myc-driven transcription. Cell Chem Biol, 2019, 26, 1-13

[4] David B. Freeman, André Richters, Marius S. Pop, Nicholas B. Struntz, and Angela N. Koehler. Emerging Non-Canonical Small Molecule Inhibitors of Androgen Receptor (AR) and AR Interactome Partners for the Treatment of Castrate-Resistant Prostate Cancer. ACS Med Chem Rev 2018, Vol. 53, Chapter 14, 267-288

[3] Nicholas B. Struntz and Daniel A. Harki. Catch and Release DNA Decoys: Capture and Photochemical Dissociation of Transcription Factors. ACS Chem Biol 2016, 11, 1631-1638 [PDF

Highlight on Nicholas B. Struntz: Introducing Our Authors - ACS Chemical Biology.

[2] Nicholas B. Struntz, Tianshun Hu, Brian R. White, Margaret E. Olson, and Daniel A. Harki. Inhibition of Guanosine Monophosphate Synthetase by the Substrate Enantiomer L-XMP. ChemBioChem 2012, 13, 2517-2520 [PDF] [Supplemental Information]

[1] Joseph K. Hexum, Rodolfo Tello-Aburto, Nicholas B. Struntz, Andrew M. Harned, and Daniel A. Harki. Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling. ACS Med Chem Lett 2012, 3, 459-464 [PDF] [Supplemental Information]

Patents

[2] David B. Freeman, Nicholas B. Struntz, Shelby K. Doyle, André Richters, and Angela N. Koehler. 2018, PCT/US2018/044204. Massachusetts Institute of Technology. Small Molecule Modulators of the Androgen Receptor.

[1] Angela N. Koehler, Eric Stefan, Francisco Caballero,  Dylan V. Neel, Nicholas B. Struntz, Helen L. Evans, and Andrew Chen. 2017, U.S. Patent No. WO201714305. Massachusetts Institute of Technology. MAX Binders as MYC Modulators and Uses Thereof.